Wednesday, July 10, 2013

2 TSRI professors named Simons Investigators

2 TSRI professors named Simons Investigators [ Back to EurekAlert! ] Public release date: 9-Jul-2013
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Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

LA JOLLA, CA July 9, 2013 Professors Donna Blackmond, PhD, and Gerald Joyce, MD, PhD, of The Scripps Research Institute (TSRI) have been named Simons Investigators for the Collaboration on the Origins of Life, sponsored by the Simons Foundation, a New York-based nonprofit organization established in 1994 to advance the frontiers of research in mathematics and basic sciences.

"Congratulations to Donna and Jerry," said Michael A. Marletta, president and CEO of The Scripps Research Institute. "Thanks to the support of the Simons Foundation, I look forward to new insights from their labs into one of our great mysteriesthe origins of life."

The 15-member international Simons collaboration aims to support creative, innovative research in 10 topic areas concerning the processes that led to the emergence of life on the planet Earth, including the development of prebiotic chemistry and RNA replication. Blackmond and Joyce each will receive $2 million of research funding from the Simons Foundation over the next five years.

Blackmond's project focuses on chiralitythe structural characteristic of a molecule that makes it impossible to superimpose it on its mirror imageand the likely prebiotic conditions that may have led to single chirality as a precursor to enhanced molecular complexity. Blackmond is a professor in the TSRI Department of Chemistry.

Joyce's project involves experimental studies that seek to determine the minimum amount of information required to provide replicating, evolving systems that have the ongoing capacity to accrue more information. Joyce is a professor in the TSRI Department of Cell and Molecular Biology.

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2 TSRI professors named Simons Investigators [ Back to EurekAlert! ] Public release date: 9-Jul-2013
[ | E-mail | Share Share ]

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

LA JOLLA, CA July 9, 2013 Professors Donna Blackmond, PhD, and Gerald Joyce, MD, PhD, of The Scripps Research Institute (TSRI) have been named Simons Investigators for the Collaboration on the Origins of Life, sponsored by the Simons Foundation, a New York-based nonprofit organization established in 1994 to advance the frontiers of research in mathematics and basic sciences.

"Congratulations to Donna and Jerry," said Michael A. Marletta, president and CEO of The Scripps Research Institute. "Thanks to the support of the Simons Foundation, I look forward to new insights from their labs into one of our great mysteriesthe origins of life."

The 15-member international Simons collaboration aims to support creative, innovative research in 10 topic areas concerning the processes that led to the emergence of life on the planet Earth, including the development of prebiotic chemistry and RNA replication. Blackmond and Joyce each will receive $2 million of research funding from the Simons Foundation over the next five years.

Blackmond's project focuses on chiralitythe structural characteristic of a molecule that makes it impossible to superimpose it on its mirror imageand the likely prebiotic conditions that may have led to single chirality as a precursor to enhanced molecular complexity. Blackmond is a professor in the TSRI Department of Chemistry.

Joyce's project involves experimental studies that seek to determine the minimum amount of information required to provide replicating, evolving systems that have the ongoing capacity to accrue more information. Joyce is a professor in the TSRI Department of Cell and Molecular Biology.

###


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-07/sri-ttp070913.php

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Source: http://www.strictlyfitteds.com/content/2013/07/metal-mulisha-x-new-eragrim-59fifty-fitted-baseball-cap

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Sony Action Cam adopted as official camera of choice for the Isle of Man TT Race 2013

The 2013 Isle of Man TT race[i] generated extra highlights this year as 47 Action Cams were fitted to the leading racers, capturing some amazing content which can now be viewed on the Sony Action Cam YouTube channel.

Designed to capture video footage from the most extraordinary of places, Action Cam brings together the best of Sony technology into a 90g body including a 16.8MP Exmor R? sensor, Image Stabilisation and Slow Motion Photography.

Christopher Coote, Producer at North One TV commented: ?We were impressed with the picture and sound quality of the Action Cam that delivered output which belied its size. We needed a camera solution which was unobtrusive but enabled us to capture the adrenalin rush experienced by the TT riders and the Action Cam fitted the bill perfectly. This is why we adopted it as the official camera of the TT Races this year.?



[i] The Isle of Man TT is a race of legend! It is one of, if not THE most challenging races in the World, and not for the faint of heart. The 37.73 miles is the ultimate test of mind, body and machine, with average speeds of 131.671 mph around this fabled mountain course, nothing can prepare you for the spectacle of the Isle of Man TT.

Source: http://presscentre.sony.eu:80//content/detail.aspx?ReleaseID=8750&NewsAreaID=2

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Tuesday, July 9, 2013

'Cosby Show' gets 'Blurred' in perfect mash-up

Pop culture

1 hour ago

Twenty years after "The Cosby Show" went off the air, Bill and his TV family still have the moves to make them suitable stand-ins for Robin Thicke's super catchy "Blurred Lines" video.

In a mash-up of the practically saintly and the definitely sexy, a new viral video replaces the opening theme song to the late-'80s sitcom with the 2013 hit from Thicke, Pharrell and T.I.

In the original, Cliff Huxtable, wife Clair, and kids Vanessa, Theo, Denise and Rudy all get down to a jazzy instrumental number ? "Kiss Me," composed by Cosby and Stu Gardner. Bill Cosby's grimace and stiff moves are lovingly juxtaposed alongside his groovier family members.

In the remake ? complete with a giant #COSBY stamp to match the #THICKE one it mimics ? the family's dance moves don't miss a beat when set to Thicke's R&B track. Every spin, arm swing and knee bend makes it seem like the actors are really dancing to "Blurred Lines."

You just can't let visions of the scantily clad models in the real Thicke video (84 million views on YouTube) re-enter your mind. And maybe don't think about the "Blurred Lines" lyrics while you watch the Cos bump up against his kids: "I know you want it, but you're a good girl. They way you grab me, must wanna get nasty ..."

An unrated version of Thicke's video would definitely not be suitable viewing at the Huxtable residence, as it contains a good deal of nudity. The singer has also had to defend the song against critics who call the lyrics "rapey."

Source: http://www.today.com/entertainment/cosby-show-meets-robin-thicke-hit-perfect-video-mash-6C10582947

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Waze could lead way to Israeli Internet growth

FILE - In this March 15, 2012 file photo, Ben Gleitzman uses a traffic and navigation app called Waze as he drives to work in Menlo Park, Calif. The record-breaking sale of Israeli navigation company Waze to Google earlier this month told the world what Israel?s tech experts have known for years: The mideast country is now a major player in Internet innovation. (AP Photo/Paul Sakuma, File)

FILE - In this March 15, 2012 file photo, Ben Gleitzman uses a traffic and navigation app called Waze as he drives to work in Menlo Park, Calif. The record-breaking sale of Israeli navigation company Waze to Google earlier this month told the world what Israel?s tech experts have known for years: The mideast country is now a major player in Internet innovation. (AP Photo/Paul Sakuma, File)

(AP) ? The billion-dollar sale of navigation company Waze to Google may finally be putting Israel on the map as a major player in consumer Internet innovation.

Israel's high-tech sector has been dominated by firms that made products for other businesses, like computer chips or communications gear. But in recent years Internet and mobile companies have emerged as the majority of Israeli startups, and many have found success in the global market.

The focus might be changing now.

"There's definitely a shift that Waze has done a great deal of emphasizing," said Nir Zohar, the president and chief operating officer of Wix. "I would assume that we will find more foreign investors coming to Israel to invest in Israeli entrepreneurs." Wix, a personal website company, filed last month for a $75 million initial public offering the United States, just as Google was wrapping up its $1.03 billion purchase of Waze.

Foreign investors are beginning to take notice.

Israeli consumer firms myheritage.com, a genealogy site, and Fiverr.com, an online marketplace for creative services, received major backing last year from Accel Partners and Bessemer, two leading American venture firms.

Veterans of the Israeli Internet startup scene say that Israeli companies are known for their creativity and international outlook, so the move into the fast-growing world of smartphone apps and consumer websites has been relatively easy.

"Because we don't have a local market, we go on the international market from day one," said Uri Adoni of Jerusalem Venture Partners, one of the leading tech investment firms in Israel.

Unlike in larger countries, he said, Israel's small size means that its startups naturally target places like the United States instead of the domestic market. With products ready-made for international use, they are attractive to overseas venture capitalists.

Experts say Israeli companies are accustomed to taking unconventional risks in building their products.

"There's always a special Israeli take, and the take is 'Let's go crazy, let's bring something that's completely off the charts,'" said Michal Adam of the IVC Research Center, which tracks statistics on Israeli venture capital.

In the case of Waze, that meant relying on the app's user base in order to help build its maps because it lacked the vast amounts of data and satellite imagery of a company like Google. Thanks to its crowdsourcing feature, Waze's mapping service provides its user community with real-time information on traffic conditions, accidents and speed traps that standard GPS services have struggled to gather. The service has also generated a loyal user base.

The Israeli way, Adam said, is "doing things simple when you need a complicated result because you don't have the money and the resources."

Roughly three-quarters of Israeli startups provide mobile or Internet services, according to IVC. Just five years ago, the number was below 50 percent.

After bottoming out in 2009 during the global financial crisis, American venture capitalists have steadily ramped up investments in Israel. Last year, according to the National Venture Capital Association in Arlington, Va., they pumped almost $85 million of equity into Israeli Internet companies, the highest amount since the global financial crisis five years ago.

Overall, Israel is the world's largest destination for high tech venture capital after Silicon Valley.

Yossi Vardi, a leading figure in the Israeli tech scene, said the Internet boom is also a result of natural growth. "Every major (acquisition) creates a wave of angels and new investors," he said. "Angels" are the individuals who make early investments in high-risk companies.

Vardi helped pave the way for the current crop of Internet firms as an original investor in ICQ, the forerunner to modern instant messaging services. When ICQ was sold to AOL for $400 million in 1998, Vardi took his profits from the deal and invested in more than 100 other tech companies, about half of them consumer oriented like ICQ. Many of those companies, like answers.com and media software maker FoxyTunes, added success stories to the Israeli consumer market.

Vardi expects that the Waze sale will spark a similar round of growth.

Along with attracting new investors, each successful new company creates a new supply of experienced employees who may go on to form startups of their own.

"In three years, there are going to be a lot of people who are employees of these companies who are going to go out into the market," said Micha Kaufman, the CEO of Fiverr.com. Alexa, an Amazon-owned web analytics service, ranks Fiverr among the 200 most visited websites in the world.

Some experts warn of overconfidence. The low costs of launching a consumer-oriented startup, which do not require factories and large machinery used by traditional companies, has made it easy for anyone with an idea to start a business. Those low costs make the companies attractive to investors, who can afford small bets on promising startups.

"I do expect more entrepreneurs to throw their hats in the ring," said Adam Fisher, the head of the Israel office of Bessemer Venture Partners, a U.S. firm. He cautioned that with few barriers to entry, the Internet market could be flooded with companies that have little chance of success.

"We welcome them, but we hope they don't misread the success of Waze," Fisher said. He pointed out that a company that develops an app or program must also figure out how to make it profitable, a problem that traditional tech companies like chip manufacturers don't have.

Still, the success of Waze generates optimism among Israeli Internet companies. "All the press that all these exits are getting ... creates confidence for future buyers," said Yaron Carni, a veteran investor and head of the Tel Aviv Angels Group.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2013-07-04-ML-Israel-Internet-Boom/id-80e2726a85744ea58b28f74509385d97

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Randy Travis in Critical Condition at Texas Hospital

Randy Travis in Critical Condition at Texas Hospital
Posted by Jeremy Thomas?on 07.08.2013

Complications from heart disease...

Country singer Randy Travis is in critical condition in a hospital in Texas. TMZ reports that Travis was admitted to the hospital yesterday after suffering from complications related to his viral cardiomyopathy, a disease that weakens and enlarges the heart muscle.

Travis was set to perform in Deadwood, South Dakota on Wednesday. No news on what caused his condition.

On behalf of 411, our best wishes for Travis' quick recovery.


comments powered by

Source: http://www.411mania.com/music/news/290034

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Service was the best i have experienced in a london restaurant ever, waiters were polite, ...

52 Wilton Road, Victoria, London, SW1V 1DE - View on a map
Telephone: 020 7828 5818

Gran Paradiso

Service was the best i have experienced in a london restaurant ever, waiters were polite, attentive and friendly. I like the oldy italian decor of the restaurant and the whole place had an edge of poshness about it. So refreshing to be made to feel like a patron rather than just walking a wallet - something unfortunately I have gotten so used to in the big chain restaurants. The tables aren't too close together and I like the choices on the menu although note the lack of a comprehensive drinks list.

The food at Gran Paradiso was lovely - my chicken in herbs and mushroom sauce was tender and tasty although as others have mentioned it seems a bit steep to charge ?4 for the vegetables to accompany it (although they were cooked to perfection and delicious).

I will most definitely be coming back here again, it's a little more expensive than other places (the chains) but it's worth it for the quality of food and excellent service.
Comment on this reader review


9 Overall rating 9 stars
Food 9 | Service 9 | Atmosphere 8 | Value for money 8
Thursday, April 11, 2013

Gran Paradiso

Understandably after reading through the negative reviews on here I attended a business dinner at this restaurant tonight, a large group of 15 people booked for 6pm but arrived late at 6.20pm. No problem from the manager and his wife.

Comments on here state the waiters were not chatty, but our experience was that they were attentive and efficient, if you want entertaining from the waiters pay for a stage show. I much prefer getting professional service!

The food could not be faulted, cooked to perfection, portion sizes just right, have eaten at many 4 and 5 star hotels who give you half the size of portions, and not necessarily as good quality as the Gran Paradiso.

Some people have said dated decor etc, but I couldn't fault the upstairs conservatory room our group had our meal in.

In summary a wonderful meal with attentive service at a reasonable price.
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Andrew Bird
10 Overall rating 10 stars
Food 10 | Service 10 | Atmosphere 10 | Value for money 10
Thursday, January 17, 2013

Gran Paradiso

I used to visit this restaurant from when it opened in 1973 for about ten years, and I am old enough to have gone to its predecessor in the King's Road under the old cinema.

So, for old times' sake, I chose it recently for dinner with friends.

It was undoubtedly old fashioned and the staff were a little shambolic, but I really enjoyed going back there. The same owner is still there after all these years, and the food was very tasty. The restaurant had a good atmosphere, with quite a few tables clearly enjoying themselves.

My wife didn't enjoy it so much, so maybe nostalgia is ruling my head. However, if you are in the area, Gran Paradiso is civilized, near to the station, with pretty good food, sufficiently out of the way to be on the quiet side and worth a visit, if not a special trip.

Long may Sandro continue!
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James - View all reviews by this user
8 Overall rating 8 stars
Food 9 | Service 7 | Atmosphere 7 | Value for money 7
Thursday, October 11, 2012

Gran Paradiso

I went to the Gran Paradiso and found the food I had was very poor considering the prices. The prawn starter lacked flavour and the pasta dish prawns and clams linguine, there was no clams in there but even worse the pasta was over cooked.

I found the service good, but the food is what I go out for.
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Will F
4 Overall rating 4 stars
Food 2 | Service 8 | Atmosphere 5 | Value for money 2
Sunday, February 26, 2012

Gran Paradiso

Sorely disappointed by this restaurant that promises nice Italian food.

The food was adequate but considering the price (around ?30 per person for starter and main) you may expect more.

What was really disappointing was the terrible service we received. Not only were the servers incredibly rude but when we raised it as an issue rather than apologise they continued to argue back.

It was very disappointing that what would have been a pleasant mid-week meal was spoiled by rude and surly service.
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May
2 Overall rating 2 stars
Food 5 | Service 0 | Atmosphere 1 | Value for money 2
Monday, October 10, 2011

Gran Paradiso

Was part of a party of four there last night. Went with some trepidation after reading some reviews on here, but overall was pleasantly surprised.

Pate to start was nice, with very nice toasted bread to complement it. Beautifully cooked lamb cutlets as a main dish. Couldn't fault the food on either taste or size of portions.

Two gripes from me ; firstly, at the prices being charged they really shouldn't be separately charging up to ?4 for a portion of vegetables.

Secondly, the general tardiness of service. It took them twenty minutes to even take the order, and when we wanted to pay and leave, again they showed little urgency. You would have thought being so close to a main railway station they would appreciate people are often looking to catch a train and get a move on.

Overall though I enjoyed it, though I'm not sure I'd go again. At the prices charged, there are far better restaurants literally down the road.
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Robert Whittaker
7 Overall rating 7 stars
Food 8 | Service 5 | Atmosphere 8 | Value for money 5
Saturday, March 26, 2011

Gran Paradiso

i had lunch with a business associate here earlier this week. quite an old restaurant in seventies styly, however, very friendly and fast service. the food was good but not fantastic, i had mushroo/truffle penne and my friend had calves liver followed by nice fresh fruit and sorbet. all in all very good but not as great as it apparently used to be. that being said scored highly on service. excellent.
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dinner64 - View all reviews by this user
7 Overall rating 7 stars
Food 5 | Service 8 | Atmosphere 7 | Value for money 6
Wednesday, January 26, 2011

Gran Paradiso

Well from outside it looks great but as soon as you walk in its like stepping back in time. This place is so dated, the crab I set next to was so dusty!

Anyway we waited 45 minutes for one prawn cocktail, which to be far was ok, not great. then the mains came, well paying ?16 on average for a main is expensive, so paying extras for the veg and potatoes was a joke. Mine was so chicken with mushrooms and was so salty, I could not eat it. Nobody approached us during the meal , so when they came to take the plates I explained the food was awful. No sorry , nothing. When the bill came the lady said yes it was wrong and took it off the bill.

Dated, miserable staff, and awful food AVOID.

Nandos across the road is better!
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Lady Smith
0 Overall rating 0 stars
Food 0 | Service 0 | Atmosphere 0 | Value for money 0
Saturday, November 20, 2010

Gran Paradiso

I agree with Jessica. This restaurant is my default for business entertaining and some occasions with close friends. The food is consistently good and the Patrone and his staff most welcoming. The prices are consistent with the quality, especially for central London. I always leave with a smile on my face from enjoying this sllgtly dowdy (and charming) but fulfilling restaurant.
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Lester
8 Overall rating 8 stars
Food 8 | Service 8 | Atmosphere 7 | Value for money 8
Thursday, November 18, 2010

Gran Paradiso

I went to Gran Paradiso last week to celebrate my grandson's 17th Birthday as well as my daughter in law's Birthday. I heard they are "good" on mushroom dishes (owner has written a book on mushrooms) We all loved the place and the food and shall return ,no doubt about that!!

The owner was present throughout as well as his charming wife...they 've had the restaurant for 40 years and of all the Italian restaurants here and in Venice, I loved this one the most!
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Irena Michalowska
10 Overall rating 10 stars
Food 10 | Service 10 | Atmosphere 10 | Value for money 10
Friday, October 29, 2010

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Source: http://www.london-eating.co.uk/3521.htm

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